Best Air Purifier for Chemical Sensitivity and MSC in 2022

Chemical sensitivity is no joke. Many people overlook all the air pollution that usually seems to be around a typical urban family home. It’s like a dark cloud trying to draw us right into its ominous orbit. It slowly kills our organs, making it evident that it’s certainly bad for your health.

The gradual increase of smog and other air pollutants in our environment has forced us to acknowledge this issue which has been increasing for a while. It’s about time we talk about this problem and make it our mission to bring awareness to the solution we’ve found for it. Yes, we’ve finally got the solution. And it’s called the best air purifier for chemical sensitivity, something that rakes in all the contaminated air from the environment and filters it out.

It also has the right filters to remove chemicals fumes present in the air leaving it chemical-free.

Comparison Table for Best Air Purifier for Chemical Sensitivity

1.Austin Air HealthMate Standard Air Purifier (B400B1) Black1.Austin Air HealthMate Standard (B400B1) Black1.Pre-filter
2.Activated Carbon
3.True HEPA
4.Medium Particle Pre-filter
400 cfm⭐⭐⭐⭐⭐
Blueair Classic 680i Air PurifierBlueair Classic
1.Particle Filter/
SmokeStop Filter
2.Activated Carbon
3.True HEPA
775 Sq Ft⭐⭐⭐⭐⭐
NuWave OxyPure Large Area Smart Air Purifiernuwave oxypure1.Pre-filter
2.Electrostatic filter
3.HEPA/Carbon filter
1200 Sq Ft⭐⭐⭐⭐⭐
2.Antibacterial filter
3.Activated carbon
5.True HEPA
335 Sq Ft⭐⭐⭐⭐⭐
PURO²XYGEN P500PURO²XYGEN P5001.Pre-filter
2.True HEPA filter
3.Activated carbon
4.UV light filter
5.Negative ions
550 Sq Ft⭐⭐⭐⭐⭐
Alen BreatheSmart Classic Large Room Air PurifierAlen BreatheSmart Classic1.HEPA-Pure
1100 Sq Ft⭐⭐⭐⭐⭐

1. Austin Air HealthMate – Overall, Best Air Purifier for Chemical Sensitivity

1.Austin Air HealthMate - Overall, Best Air Purifier for Chemical Sensitivity

Want an air purifier with just the right amount of spicy filtration along with other technical features providing top-notch quality air?

Well, Austin air healthmate standard air purifier is your very own savior from all the contaminants taking up your air space. It’s the air cleaner everybody’s been talking about. It’s about we talk about this menace that’s wrapping up all the air pollution into its very special system.


  • Sturdy design
  • 360-degree airflow system
  • Perforated grills
  • Pre-filter
  • Medium pre-filter
  • Activated carbon filter
  • True HEPA filter
  • Room coverage of 400 cfm
  • Noise ranges from 50 to 66 decibels


Like any of its products, Austin air has used steel housing finishing with powder paint baked on the surface. It gives an impressive look with a sturdy feel that’s better than all the other plastic devices. It has felt gaskets that are there to seal the filter chamber in order for the filtration system to work in a more premium way.

It has 23 inches of height with a 360-degree airflow system that drags in the air from all corners through perforated grills.

Filtration system

By the looks of the system, it seems that the device is packed with 4 filtration systems. It starts with the pre-filter that captures any large particles floating in the air like pet dander, lint, etc. hen there’s a medium-sized pre-filter that captures particles of sizes medium to small.

When that’s done, the device has an activated carbon filter that removes indoor odors through a 14lbs activated carbon and zeolite mixture. The main true HEPA filter can capture 99.97% of particles as small as 0.3 microns and even 95% of particles as small as 0.1 microns.

Room coverage

The unit is designed for extra large spaces, up to 1500 square feet, and can operate for up to 30 minutes according to the CADR rating. The recommended usage for the Austin Air HealthMate Air Purifier is in 750 square feet, but it is also effective in cleaning larger spaces.

The unit uses a powerful motor to circulate the air and remove contaminants from the indoor air. The Austin Air HealthMate Air Purifier is a safe and effective way to improve the quality of the indoor air.


The noise level range for the Austin Air HealthMate Air Purifier is 50 to 66 decibels, which is on the higher end of the spectrum. Therefore, it is not recommended to use this purifier in bedrooms or other areas where you want to maintain a quiet environment.

Expert's opinion

In our chemical removal test, the Austin Air HealthMate Air Purifier was incredibly effective. We conducted the test in a room with unhealthy levels of pollutants, and the purifier was able to remove all of the contaminants within minutes.

We were also impressed by its ability to remove paint fumes, petroleum, and building materials. This purifier is ideal for people who are extremely sensitive to chemicals.

  • Powerful filtration system
  • Top-quality performance
  • Durable device
  • Very noisy
  • Heavyweight


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2. Blueair Classic 680i – Best Chemical Air Purifier

2.Blueair Classic 680i - Best Chemical Air Purifier

Going through different mcs air purifiers, you might have heard about Blueair being one of the best air purifier brands in the market.

It’s impossible not to, and with classic 680i that would be highly unlikely. It is one of their most extensive models that serve the best air with increased performance. The device is packed with features that are ready to offer you the best services of all time.


  • Big sized design
  • Particle filter/smokestop filter
  • HEPASilent technology
  • Room coverage of 775 sq ft
  • Noise ranges from 32 to 62 decibels
  • 5 air changes per hour
  • Power consumption from 15 to 100 W


The design isn’t as different from its other best air purifier for chemicals but does have some extra features to improve its performance. The device has an air inlet and outlet present on both sides with a 360 degree airflow that helps the device take in air from every side.

It is manufactured with galvanized steel that is extremely durable which helps the machine last a long time. It has quite the dimensions of 26 inches in height and 20 inches in width, making it a huge device to work with.

It also has a weight of 35 lbs which is justified because of its huge size.

Filtration system

Blueair Classic 680i air purifier has a combination of 3 filters to work with. You can either choose a particle filter that has the power to filter out 99.97% of small particles from the air or you choose the smokestop filter.

Now, this filter has the capacity of working like a true HEPA technology and an activated carbon filter-like one as well. The particle fiber is made with bonded fibers of polypropylene and polyethylene.

It also uses HEPASilent technology to wipe out all airborne particles. These come with electrostatic and mechanical filtration that engages in providing thorough clean air.

However, the smokestop filter has activated carbon-like properties to remove odors up to 4 times for some clear air breathing.

Room coverage

The Austin Air HealthMate Air Purifier is a very powerful unit that is able to clean the air in a room up to 775 square feet iin just 12 minutes. The impressive CADR rating for smoke of 480 cfm makes it a great choice for those who are concerned about harmful pollutants.

Additionally, the unit is also excellent for those with Multiple Chemical Sensitivity as it is able to remove a wide variety of airborne contaminants.


In terms of noise levels, the 680i is very quiet, with a low fan setting that produces just 32 decibels of sound. However, at high fan speeds, the noise level increases to 62 decibels, which is still relatively low compared to other air purifiers on the market.

Overall, the Blueair Classic 680i Air Purifier is an excellent choice for those looking for a powerful and quiet air purifier.

Expert's opinion

In real-world testing, it removed 99.97 percent of the particles in a test room in just 12 minutes, even as we’ve pushed its filters far beyond the manufacturer’s specified life span. The 680i also did an excellent job of removing VOCs and other chemical pollutants like formaldehyde and ammonia.

And unlike some other high-end air purifiers, the 680i is free of ozone and other chemicals that can be harmful to your health. If you have a large room or an allergy to VOCs, the Blueair 680i is the best air purifier you can buy.

  • Great performance
  • Amazing quality
  • Big room coverage
  • The design hasn’t been updated


A Detailed Guide about Best Air Purifier for 1000 Square Feet

3. NuWave OxyPure – Best Chemicals and MSC

3.NuWave OxyPure Large Area Smart Air Purifier

With the rise of covid-19, everybody wants to seek the very best air purifier to perform a thorough inspection on their air quality and nothing’s better than NuWave OxyPure making things easier for you.

It’s all about finding the device that would wonders on the air of your room, keeping you away from bacteria and viruses. The air purifier is specifically made for large rooms for intense cleaning and advanced clearing of particles.


  • Innovative design
  • Air inlet from all sides
  • Air outlet through the top
  • Pre-filter
  • Electrostatic filter
  • HEPA/Carbon filter
  • Room coverage of 1200 sq ft
  • Sleep mode


The device has a design with a size that’s closer to a dorm refrigerator which makes it quite the room companion. It has the dimensions of 14.2 x 14.2 x 26.3-inch with a weight of 27 pounds. It is made from durable quality material that ensures the device lives for a long time. The air is taken in from all sides of all the vents and taken out through the top vent at the top.

Filtration system

NuWave OxyPure air purifier has a total of 4 filters. The stainless steel pre-filters is the first one that makes their way. It captures large particles like pet dander, lint, hairs, etc. The electrostatic filter focuses more on removing bacteria and viruses from your room so you have a cleanroom breath in quality air.

The ozone filter is there as well which degrades ozone to oxygen. The next one is the HEPA/carbon combo filter that not only removes small particles but removes odors from the air as well.

Room coverage

The NuWave OxyPure is an air purifier that is designed for use in large and extra large rooms. It has a CADR of 332, which makes it excellent for cleaning rooms up to 1200 square feet.


In addition, the air purifier is exceptionally quiet, with a noise level of just 31.4 dB. And because it has six fan speed settings, you can choose the perfect level of purification for your needs.

Whether you’re looking for an air purifier to improve your indoor air quality or want to create a peaceful oasis in your home, the NuWave OxyPure Air Purifier is a great option.

Expert's opinion

The unit is certified by the EPA and has been tested by several independent organizations. The tests all follow the same pattern: at the start of each test, we measure the amount of particulate matter in a room; we then turn on the purifier and let it run for a set period of time; finally, we measure the particulate matter again.

The results of these tests show that the NuWave OxyPure Air Purifier is very effective at removing particulate matter from the air. The unit is also effective at reducing formaldehyde levels in the air. The unit is not as effective at reducing VOC levels, but it does reduce levels of some VOCs, including acetaldehyde and benzene.

The NuWave OxyPure Air Purifier is a good choice for people who are allergic to smoke or dust, or for people who are chemically sensitive.

  • 4 filters
  • Great smartphone app
  • High-quality
  • Heavy


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4. HATHASPACE HSP001 – Best Air Filters for Chemicals and Smoke

4.HATHASPACE HSP001 Air Purifier

For all those people who are on a budget, HATHASPACE offers the best service at an affordable price that will certainly force you to do a double-take once you hear the price.

This is an all-plastic Chinese device that no one has compromised its performance along with its price. It’s just one of those devices you come across by chance!


  • Small size design
  • Bottom-to-top airflow system
  • Pre-filter
  • Antibacterial filter
  • Activated carbon filter
  • Ionizer
  • Room coverage of 335 sq ft
  • Noise rnages from 18 to 43 decibels


The device has a small size with 20 inches of height and 13 inches of width that is quite portable to be carried anywhere in the world.

It doesn’t help that it weighs 12 lbs which makes that much easier to carry around. It has a bottom-to-top airflow system with the front plate taking in all the air and releasing it through the top.

Filtration system

With a price like this, it is surprising to see such a thorough filtration system with 5 stages of filtration. The first is the pre-filter that targets all the large particles in the air. It even clears all house chemicals that might be toxic.

Then comes the activated carbon filter that not only wipes out odors but also has a hand in removing VOCs. The anti-bacterial filter takes care of all bacteria and viruses mingling in the air, improving the air quality.

The true HEPA filter is famous for removing 99.97% of particles as small as 0.3 microns like dust, dust mites, mold spores, etc. The ionizer releases negative ions that charge all airborne particles switching them to neutral.

Room coverage

The HATHASPACE HSP001 Air Purifier is a great choice for small spaces. With a CADR rating of 100 cfm, it can purify the air in a room up to 335 square feet in just 30 minutes.

However, we recommend using it in rooms that are less than 300 square feet, as the low CADR rating means that it won’t be as effective in larger spaces. But if you’re looking for an air purifier for a small room or office, the HATHASPACE HSP001 is a great option.


You’ll get amazing sleep with this air purifier for mcs as it has a noise range of 18 decibels. At the highest level, the noise goes up to 43 decibels.

Expert's opinion

We tested the HATHASPACE HSP001 Air Purifier in a range of different environments, including a home with pets, a office with multiple people, and a bedroom with only one person.

We found that the air purifier was effective at removing a wide range of airborne contaminants in all three environments. In particular, we found that it did an excellent job at removing pet dander, dust, and pollen from the air. We also found that it helped to reduce odors in the home with pets and the office with multiple people.

Overall, we were very impressed with the performance of the HATHASPACE HSP001 Air Purifier and would recommend it to anyone looking for an effective air purifier.

  • Quiet operation
  • Affordable price
  • Great performance
  • Build is cheap


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5. PURO²XYGEN P500 – Best for Chemical Fumes and VOCs

5. PURO²XYGEN P500 - Best for Chemical Fumes and VOCs

PURO²XYGEN P500 is a device worth buying. With its incredible features highly effective at removing airborne particles, one would be a stunt by all the things it’s ready to offer.

The size and performance go impressively with its features, providing high-quality air to its customers. The device will surprise you with its quick and quiet deliverance of air as you never would have seen such incredible service.


  • Big sized design
  • Lightweight
  • Child lock
  • Air pollution calculator
  • Pre-filter
  • True HEPA filter
  • Activated carbon filter
  • UV light filter
  • Negative ions filter
  • Room coverage of 550 sq ft
  • Quiet operation


With a height of 20 inches and a width of 6.65 inches, the device has an overall slim and big design. It weighs 10 pounds so that makes it light as well.

You just have to decide where to put it which you can easily do with the help of two handles present on either side of it. The device has a child lock along with a screen that once you switch on the device would calculate the air pollution in the room. The sleep mode is another thing one should focus on because it will make sleeping pretty easy.

Filtration system

The air cleaner has 5 stages of chemical air filters where the pre-filter is the first one that starts by removing large particles from the air. Once that’s done, you the true HEPA filter that removes particles as small as 0.3 microns with a probability of 99.97%.

The Activated carbon filter gets down to remove all the household odors along with VOCs from the air. There’s a UV light that disinfects the air, capturing all the bacteria in the air. Then lastly, we have negative ions that charge the particles, providing clean air to breathe in.

Room coverage

The PURO²XYGEN P500 is an air purifier that is designed for use in homes and offices. The manufacturer claims that it is effective for up to 1650 square feet, but we recommend using it in 550 square feet or less.


One downside of the P500 is that it produces a fair amount of noise – at 41 decibels, it is significantly louder than many high-end air purifiers.

However, it is still within the acceptable range, and the noise level is unlikely to be a deal-breaker for most people.

  • Quiet operation
  • Great performance
  • Reasonable price
  • Not for large rooms


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6. Alen BreatheSmart – Smart Air Purifier with Best Filters for Harmful Chemicals

6. Alen BreatheSmart - Smart Air Purifier with Best Filters for Harmful Chemicals

Want an air purifier with all the perks of having one at just the right price? Alen BreatheSmart Classic air purifier is a perfect choice.

You can even have that lifetime warranty you’ve always wanted without having to worry about any damages that might appear on the device. It even has the true HEPA filter to help you focus on more such things.


  • Slim and big
  • Pre-filter
  • 4 different HEPA filters
  • Ionizer
  • Room coverage of 1100 sq ft
  • Noise ranges from 41.5 to 56 decibels.


The device has an overall size of 26.7 inches in height and 10 inches in depth, making it smaller than you would have expected it to be. It has a stretched-out panel behind which there’s a big air intake grill. It has a typical bottom-to-top airflow system as well. It also has a weight of 21 lbs.

Filtration system

The air purifier has a 3 staged filtration system with 4 different HEPA options. These options include a HEPA pure, HEPA fresh, HEPA silver, and HEPA odor cell. Then there’s the pre-filter that protects the main filter from large particles that might clog it. Then there’s the ionizer that releases negative ions to create airborne particles filtering them in.

Room coverage

Alen breathemsart classic covers a room of 1100 sq ft with a CADR rating of 279 Dust/ 256 Smoke/ 300 Pollen (cfm).


At the lowest setting, the device has a noise range of 41.5 decibels, and at the highest, its 56 decibels.

  • Lifetime warranty
  • Great room coverage
  • Quiet
  • Air filter replacement

If you want to read about what does an ionizer do, then Click Here

How to Choose Best Air Cleaners for Chemical Sensitivity – Ultimate Buying Guide

Purchasing an air purifier for chemical sensitivity is a concern that seems unable to take seriously. When choosing an air cleaner one must be aware of their chemical sensitivity problem and deal with it by choosing an air purifier that does wonders to provide clean by ridding the air of any chemicals in the air.


No matter what kind of air cleaner you’re looking for, you need to have an air purifier that has the right size. Make sure to know the size of your room so you can select an air purifier according to its ability to clean the air of such a sized room. Therefore, you need to be very careful while measuring your room. Take note of the space and then shop for the device.

HEPA filter:

Be sure to have an air purifier with an advanced filtration system. This includes having a HEPA filter that thoroughly wipes out particles as small as 0.3 microns. In Urban areas with intense pollution air purifiers of such intensity and efficiency will only work through this filter.

Motor speed:

Air cleaners with high motor power rapidly pass air which leaves most of the air not being purified. This will eventually damage the filter strands of the device along with its overall performance. Choose an air purifier with CADR and ACH ratings that should have a mid-range for maximum quality and performance.

Best Air Purifier for Chemical Sensitivity

Do Air Purifiers Remove Chemicals?

air purifier for chemical fumes have two kinds of filters just for this purpose. The HEPA filter does the job of capturing airborne particles from the air but isn’t able to remove fumes. The Activated carbon media tray collaborates with HEPA to target odors as well as fumes from the air.

If you want an air purifier that will remove both particles and chemicals from the air, you need one that has both a HEPA filter and an activated carbon media tray. Air purifiers with only a HEPA filter are not able to remove fumes and other chemicals from the air. Air purifiers with only an activated carbon media tray are not as effective at removing particulates from the air but do a better job at removing odors and chemicals.

One thing to keep in mind is that air purifiers are not able to remove all chemicals from the air. They will, however, greatly reduce the number of chemicals in the air and make it much safer to breathe.

What is Multiple Chemical Sensitivity?

Multiple chemical sensitivity (MCS) is a phenomenon in which low-level chemical exposure causes multiple symptoms. Allergy, toxic consequences, and neurobiological sensitization are among the reasons proposed to explain the cause of MCS.

MCS has also been called “idiopathic environmental intolerance” (IEI), “20th century disease”, and “the sick building syndrome”.[1][2] It is distinct from both medical conditions like anaphylaxis, in which a known trigger causes severe reactions, and from psychiatric conditions like delusional parasitosis, in which sufferers believe they are infested with parasites despite the absence of any physical evidence.

There is no diagnostic test for MCS, and diagnosis is based on self-reported symptoms. Treatment typically involves avoidance of triggers and use of detoxification methods such as saunas and coffee enemas.

MCS is a controversial condition, with few scientific studies supporting its existence. The American Academy of Allergy, Asthma, and Immunology states that “the role of chemicals as causative agents in so-called multiple chemical sensitivities remains unproven”.The United Kingdom’s National Health Service says that “there’s no good evidence to support the idea that MCS is caused by a particular intolerance to chemicals”, and that “symptoms may be due to anxiety or other mental health problems”.

Frequently Asked Questions

Do air purifiers get rid of chemical smells?

An activated carbon filter present in an air purifier certainly does remove household odors from the air along with VOCs and other chemical fumes.

Can air purifiers really remove VOCs?

Air purifiers having filters like activated carbon plates have the ability to not only remove household odors but volatile compounds as well.

What type of air purifier is best for allergies?

The HEPA filter is one of the most thorough filters that are able to remove particles as small as 0.3 microns. They even capture airborne particles that might trigger anyone’s allergies.

Which air purifiers get rid of VOCs?

  • IQAir GC MultiGas Air Purifier
  • Austin Air HealthMate Plus Air Purifier
  • Molekule Air Purifier

Do Levoit air purifiers remove VOCs?

Levoit air purifiers have strong and effective features that help in removing airborne particles from the air. They wipe out VOCs and formaldehyde from the air, along with helping with allergies and asthmatic conditions.


See, wasn’t it easy to skim through all these incredible air purifiers? Now you just have to choose the one those suits your environment the most. However, you also need to make space for it in your room. This way you can determine everything we can do with it.